李硕,博士,研究员
个人简历
李硕,研究员,硕士研究生导师,1984年生,山东淄博人,现为植物病毒研究室副主任。2012年毕业于南京农业大学植物病理学专业,获农学博士学位,同年进入江苏省农科院植保所工作,研究方向为昆虫介体传播植物病毒机理及介体控制技术。主持国家自然科学基金、江苏省自然科学基金等项目5项,参加完成多项省部级课题。发表学术论文30余篇,其中以第一作者(共一)、通讯作者发表SCI论文15篇,授权发明专利1件。作为主要完成人获得国家科技进步奖二等奖、教育部高等学校科技进步奖一等奖和中华农业科技奖二等奖。入选农业农村部“杰出青年农业科学家”和江苏省第五期“333高层次人才工程”第三层次培养对象(中青年学术技术带头人)。
办公电话:025-84390394, Email:lishuo@jaas.ac.cn
人才称号
1.2018年,入选农业农村部“杰出青年农业科学家”;
2.2018年,入选江苏省第五期“333高层次人才培养工程”培养对象(中青年学术技术带头人)。
科技成果奖励
1.水稻条纹叶枯病和黑条矮缩病灾变规律与绿色防控技术,2016年度国家科学技术进步奖二等奖,第八完成人,奖励部门:国务院;
2.灰飞虱传水稻条纹叶枯病灾变规律与绿色防控技术,2015年度高等学校科技进步奖一等奖,第七完成人,奖励部门:教育部;
3.水稻条纹叶枯病灾变规律与持续控制技术,2012-2013年度中华农业科技奖二等奖,第七完成人,奖励部门:农业部;
4.Five proteins of Laodelphax striatellus are potentially involved in the interactions between Rice stripe virus and vector,南京市第十届自然科学优秀学术论文奖二等奖,第一完成人,奖励部门:南京市人民政府;
5.粳稻区水稻黑条矮缩病暴发成因与防控关键技术,2013年度江苏省农业科学院科学技术奖一等奖,第十完成人,奖励部门:江苏省农科院。
主持科研项目
1. 国家自然科学基金青年基金(31601611),水稻黑条矮缩病毒P6和P9-1蛋白抑制灰飞虱RNAi免疫机理,2017-2019;
2. 江苏省自然科学基金面上项目(BK20151363),水稻黑条矮缩病毒P6和P9-1蛋白抑制灰飞虱RNAi免疫机理,2015-2018;
3. 江苏省农业科技自主创新项目(CX[14]5019),灰飞虱膜蛋白GN-Rp在传播水稻条纹病毒过程中的关键作用,2014-2016;
4. 农产品质量安全危害因子与风险防控国家重点实验室(筹)开放课题(KF20190102),利用天然产物抑制昆虫传播植物病毒研究,2019-2020。
发表论文
2020年
Xu C, Lu C, Piao J, Wang Y, Zhou T, Zhou Y, Li S*. Rice virus release from the planthopper salivary gland is independent of plant tissue recognition by the stylet. Pest Management Science, 2020, online, doi: 10.1002/ps.5876. (*通讯作者)
He P*, Wang M, Wang H, Ma Y, Yang S, Li S, Li X, Li S, Zhang F, Wang Q, Ran H, Yang G, Dewer Y, He M. Genome-wide identification of chemosensory receptor genes in the small brown planthopper, Laodelphax striatellus. Genomics, 2020, 112: 2034-2040.
Lu R, Liu Z, Shao Y, Su J, Li X, Sun F, Zhang Y, Li S, Zhang Y, Cui J, Zhou Y, Shen W*, Zhou T*. Nitric oxide enhances rice resistance to Rice black-streaked dwarf virus infection. Rice, 2020, 13: 24.
2019年
Li S*. Regulation of ribosomal proteins on viral infection. Cells, 2019, 8: 508.
Li S*, Zhou C, Zhou Y. Olfactory co-receptor Orco stimulated by Rice stripe virus is essential for host seeking behavior in small brown planthopper. Pest Management Science, 2019, 75: 187-194.
Lu G, Li S, Zhou C, Qian X, Xiang Q, Yang T, Wu J, Zhou X, Zhou Y, Ding X, Tao X*. Tenuivirus utilizes its glycoprotein as a helper component to overcome insect midgut barriers for its circulative and propagative transmission. PLoS Pathogens, 2019, 15(3): e1007655.
朴君, 许春玲, 朴敬爱, 周益军, 李硕*. 灰飞虱内生病毒HiPV外壳蛋白VP1多克隆抗体的制备及在病毒检测中的应用. 昆虫学报, 2019, 62(7): 823-829. (*通讯作者)
He P*, Chen G, Li S, Wang J, Ma Y, Pan Y, He M. Evolution and functional analysis of odorantbinding proteins in three rice planthoppers: Nilaparvata lugens, Sogatella furcifera, and Laodelphax striatellus. Pest Management Science, 2019, 75: 1606-1620.
2018年
Li S*, Li X, Zhou Y*. Ribosomal protein L18 is an essential factor that promote rice stripe virus accumulation in small brown planthopper. Virus Research, 2018, 247: 15-20.
Zhou C, Li S*, Zhou Y, Fan Y*. A simple method for obtaining rice black-streaked dwarf virus-infected small brown planthopper nymphs. Journal of Virological Methods, 2018, 251: 80-82. (*通讯作者)
Zhao W, Ji Y, Wu S, Ma X, Li S, Sun F, Cheng Z, Zhou Y*, Fan Y*. Single amino acid in V2 encoded by TYLCV is responsible for its self-interaction, aggregates and pathogenicity. Scientific Reports, 2018, 8: 3561.
2017年
Li S*, Zhou C, Chen G, Zhou Y*. Bacterial microbiota in small brown planthopper populations with different rice viruses. Journal of Basic Microbiology, 2017, 57: 590-596.
Fang Y, Choi JY, Lee SH, Kim JH, Park DH, Park MG, Woo RM, Lee BR, Kim WJ, Li S, Je YH. RNA interference of E75 nuclear receptor gene suppresses transmission of rice stripe virus in Laodelphax striatellus. Journal of Asia-Pacific Entomology, 2017, 20: 1140-1144.
2015年
Li S, Wang S, Wang X, Li X, Zi J, Ge S, Cheng Z, Zhou T, Ji Y, Deng J, Wong S, Zhou Y*. Rice stripe virus affects the viability of its vector offspring by changing developmental gene expression in embryos. Scientific Reports, 2015, 5: 7883.
Li S, Ge S, Wang X, Sun L, Liu Z*, Zhou Y*. Facilitation of Rice stripe virus accumulation in the insect vector by Himetobi P virus VP1. Viruses, 2015, 7: 1492-1504.
Li S, Wang X, Xu J, Ji Y, Zhou Y*. A simplified method for simultaneous detection of Rice stripe virus and Rice black-streaked dwarf virus in insect vector. Journal of Virological Methods, 2015, 211: 32-35.
He M, Jiang Z, Li S*, He P*. Presence of Poly(A) tails at the 3'-termini of some mRNAs of a double-stranded RNA virus, Southern rice black-streaked dwarf virus. Viruses, 2015, 7: 1642-1650. (*通讯作者)
2014年
Yao M#, Liu X#, Li S#, Xu Y#, Zhou Y, Zhou X, Tao, X*. Rice stripe tenuivirus NSvc2 glycoproteins targeted to Golgi body by N-terminal transmembrane domain and adjacent cytosolic 24 amino-acids via COP I-and COP II-dependent secretion pathway. Journal of Virology, 2014, 88(6): 3223-3234. (#共同一作)
李硕,王世娟,訾金燕,王喜,周益军. 灰飞虱从离体病叶快速获得水稻条纹病毒的方法. 江苏农业学报, 2014, 30(2): 449-451.
徐秋芳,陈晴晴,倪海平,李硕,张金凤,周益军. 灰飞虱原肌球蛋白的基因克隆、原核表达及多克隆抗体制备. 中国农业科学, 2014, 47: 3791-3798.
陈晴晴,李艳舞,倪海平,徐秋芳,张金凤,李硕,周益军. 灰飞虱actin基因的克隆及原核表达. 江苏农业学报, 2014, 30: 1010-1014.
2013年
Deng J#, Li S#, Hong J, Ji Y, Zhou Y*. Investigation on subcellular localization of Rice stripe virus in its vector small brown planthopper by electron microscopy. Virology Journal, 2013, 10: 310. (#共同一作)
Cheng Z#, Li S#, Gao R, Sun F, Liu W, Zhou G, Wu J, Zhou X, Zhou Y*. Distribution and genetic diversity of Southern rice black-streaked dwarf virus inChina. Virology Journal, 2013, 10: 307. (#共同一作)
Zhang Y, Li S, Xu L, Guo H, Zi J, Wang L, He P, Fang J*. Overexpression of carboxylesterase-1 and mutation (F439H) of acetylcholinesterase-1 are associated with chlorpyrifos resistance in Laodelphax striatellus. Pesticide Biochemistry and Physiology, 2013, 106: 8-13.
徐秋芳,陈晴晴,张金凤,李硕,倪海平,周益军. 酵母双杂交筛选灰飞虱体内水稻黑条矮缩病毒p10的互作蛋白. 中国水稻科学, 2013, 27: 633-638.
2012年
Li S, Li X, Sun L, Zhou Y*. Analysis of rice stripe virus whole-gene expression in rice and in the small brown planthopper by real-time quantitative PCR. Acta Virologica, 2012, 56(1): 67-71.
Zhang Y, Guo H, Yang Q, Li S, Wang L, Zhang G, Fang J*. Overexpression of a P450 gene (CYP6CW1) in buprofezin-resistant Laodelphax striatellus (Fallén). Pesticide Biochemistry and Physiology, 2012, 104: 277-282.
周益军*,李硕,程兆榜,周彤,范永坚. 中国水稻条纹叶枯病的研究进展. 江苏农业学报, 2012, 28(5): 1007-1015.
2011年
Li S, Xiong R, Wang X, Zhou Y*. Five proteins of Laodelphax striatellus are potentially involved in the interactions between rice stripe virus and vector. PLoS One, 2011, 6(10): e26585.
李硕,孙丽娟,李醒,熊如意,徐秋芳,周益军*. 灰飞虱高带毒(RSV)群体酵母双杂交cDNA文库的构建. 昆虫学报, 2011, 54(11): 1324-1328.